# Date Presenter Name Talk Title
1 May 22, 2018 Ruiwen Zhang, MD, PhD, DABT, FAAAS
Professor of Pharmacology and Toxicology
Robert L. Boblitt Endowed Professor in Drug Discovery
Director of UH Center for Drug Discovery
Targeting p53-MDM2 pathway: implication in cancer and neurogenerative diseases
2 April 25, 2018 Velvet (Blair) Journigan, PhD

Assistant Professor of Medicinal Chemistry

Department of Pharmaceutical Sciences

Marshall University School of Pharmacy

Structure-based design of novel small molecule ligands for the transient receptor potential melastatin 8 (TRPM8) ion channel: Insights and applications from recent structural biology advances.
3 March 21, 2018 Mary Torregrossa, PhD

Assoc. Prof., Psychiatry, Translational Neuroscience Program, University of Pittsburgh

Identification of Novel Regulators of Cocaine-Associated Memories.


4 January 8, 2018 Inmaculada (Inma) Hernandez, PharmD, PhD

Assistant Professor

Department of Pharmaceutical Sciences

University of Pittsburgh

Real-world Use, Outcomes, and (Value-based?) Pricing of Pharmaceuticals: An Overview of My Research Program.


5 January 8, 2018 Philip Empey, PharmD, PhD

Assistant Professor

Department of Pharmaceutical Sciences

University of Pittsburgh

Pharmacogenomics to achieve precision medicine at Pitt/UPMC.


6 December 11, 2017 Andreas Pfenning, PhD

Assistant Professor

Department of Computational Biology

Carnegie Mellon University

Interpreting addiction-associated genetic variation at regulatory elements.


7 November 10, 2017 Min Xu, PhD

Research Assistant Professor

Department of Computational Biology

Carnegie Mellon University

Structural mining in cellular electron cryo-tomograms


8 October 12, 2017 Zachary Freyberg, PhD

Assistant Professor

Departments of Psychiatry and Cell Biology

University of Pittsburgh

New Cryo-EM Approaches to the Study of Secretory Cell Biology


9 May 2, 2017 Robert Roth, PhD, DABT

Professor of Pharmacology and Toxicology

Director, Graduate Program in Environmental and Integrative Toxicological Sciences

Michigan State University

Drug-cytokine interaction in idiosyncratic, drug-delivered liver injury
10 April 24, 2017 Xiaoyuan (Shawn) Chen, PhD

Senior Investigator and Chief

Laboratory of Molecular and Nanomedicine

National Institute of Biomedical Imaging and Bioengineering

National Institutes of Health

Nanomedicine for imaging and therapy
11 April 18, 2017 Ram Mahato, PhD

Professor and Chair

Department of Pharmaceutical Sciences

University of Nebraska Medical Center

Gene and stem cell therapy for improving islet transplantation in humanized mice
12 April 13, 2017 Robert A. Sweet, MD

UPMC Endowed Chair & Prof., Psychiatric Neuroscience and Neurology

Investigating the Mechanisms of Psychosis
13 April 11, 2017 Susan Slaugenhaupt, PhD

Professor of Neurology

Center for Human Genetic Research

Massachusetts General Hospital

Harvard Medical School

Developing a drug for an mRNA splicing disease
14 April 4, 2017 Aiming Yu, PhD


Director of the PK/PD Bioanalytical Core Facility

Department of Biochemistry and Molecular Medicine

UC Davis School of Medicine

Translating microRNA pharmacoepigenetics into therapy
15 March 14, 2017 Seth Corey, MD, PhD

Professor and Chief

Children’s Hospital Foundation

Endowed Chair in pediatric Cancer Research

Virginia Commonwealth University

School of Medicine

Pediatric Myelodysplastic Syndromes: A Gain of Clones
16 March 3, 2017 Howard Gutstein, PhD

Peter & Eva Safar Prof. and Chair, Anesthiology, UPitt

Zero Tolerance for Chronic Pain
17 February 17, 2017 Ming Hu, PhD

Professor of Pharmaceutics

Department of Pharmacological & Pharmaceutical Sciences

University of Houston College of Pharmacy

Challenges facing CNS delivery of polyphenols and flavonoids
18 February 14, 2017 Edward Prochownik, MD, PhD

The Paul C. Gaffney Professor of Pediatrics and Professor of Microbiology & Molecular Genetics Section of Hematology/Oncology

Rangos Research Center

University of Pittsburgh

School of Medicine

Cancer as a Ribosomopathy
19 January 23, 2017


Nicholas Meanwell, PhD

Executive Director

Department of Medicinal Chemistry

Bristol-Myers Squibb

Pharmaceutical Research and Development

NS5A inhibitors of hepatitis C


20 December 13, 2016 Nathan A. Yates

Associate Professor, Department of Cell Biology

Scientific Director, Biomedical Mass Spectrometry Center

Schools of the Health Sciences

University of Pittsburgh

Application of Differential Mass Spectrometry for the Unbiased Identification of CSF Biomarkers and Novel Protein Targets
21 December 13, 2016 Jacob D. Durrant, PhD

Assistant Professor

Department of Biological Sciences

University of Pittsburgh

Computer-Aided Drug Design: From Basic Science to Clinical Applications


22 December 8, 2016 Dandan Sun, MD, PhD


Department of Neurology

School of Medicine

University of Pittsburgh

Ion transporters: new targets for glioma therapy
23 November 29, 2016 Min You, PhD


Department of Pharmaceutical Sciences

College of Pharmacy

Northeastern Ohio Medical University

Lipin-1 signaling and its implications in the alcoholic fatty liver
24 November 8, 2016 Dharini Shah, PhD

Principal Scientist

Center for Therapeutic Innovation


Adventures in drug discovery: Case studies on immune checkpoint as therapies
25 November 1, 2016 Edward A. Burton, MD, DPhil FRCP

Associate Professor of Neurology, Microbiology and Molecular Genetics

UPMC Endowed Chair in Movement Disorders

University of Pittsburgh

School of Medicine

Drug discovery for neurodegenerative diseases using novel zebrafish models
26 October 11, 2016 Gavin Arteel, PhD

Professor, Associate Chair for Research

Department of Pharmacology and Toxicology

University of Louisville School of Medicine

Transitional changes to the hepatic “matrisome” in the development of inflammatory liver injury
27 October 4, 2016 Moses Turkle Bility, PhD

Assistant Professor

Department of Infectious Diseases and Microbiology

Graduate School of Public Health

University of Pittsburgh

Modeling human pharmacogenomics in humanized mice
28 September 27, 2016 Dexing Zeng, PhD

Professor, Molecular Imaging Laboratory

Department of Medicine

University of Pittsburgh

Dual-receptor targeting for enhance PET imaging
29 September 7, 2016 Raman Venkataramanan, PhD


Dept. of Pharmaceutical Sciences, School of Pharmacy

Dept. of Pathology, School of Medicine

University of Pittsburgh

Modeling of PK and PD data in clinical pharmacology
30 August 8, 2016 Christopher K. Surratt, Professor of Pharmacology, Mylan School of Pharmacy, Duquesne University Do the behavioral effects of dopamine transporter (DAT) inhibitors correlate with DAT conformation preference?
31 August 8, 2016 Kevin Xiao, Associate Professor, Department of Pharmacology and Chemical Biology, University of Pittsburgh Defining the Higher Order Structures of  GPCR Signaling Complexes for Drug Discovery
32 August 8, 2016 Joshua Yohannan, MS, Laboratory Manager of The Allegheny County Medical Examiner’s Office AB vs. ADB: One Methyl Makes a Large Difference
33 August 8, 2016 Manojkumar Puthenveedu, Associate Professor, Biological Sciences and The Center for the Neural Basis of Cognition, Carnegie Mellon University New strategies to manage opioid addiction and pain
34 August 8, 2016 Sally E. Wenzel, Professor of Medicine & Director of University of Pittsburgh Asthma Institute @ UPMC/UPSOM 2-Adrenergic Receptor Responses and Asthma:   Modulation through Protein-Lipid Interactions
35 August 8, 2016 Youhua Liu, Professor, Department of Pathology, University of Pittsburgh Targeting Cannabinoid Receptor-2 to Reduce Renal Fibrosis
36 August 8, 2016 Rao Rapaka, Branch Chief of NIH NIDA NIDA’s Basic Chemistry Research and Translational Areas of Interest
37 August 8, 2016 Steven D. Shapiro,

Executive Vice President, UPMC

Chief Medical and Scientific Officer

UPMC’s Big Data Initiative
38 August 8, 2016 Christopher Waller, Executive Director of MRLIT Modeling Platforms

and CORE at Merck

Translational Data Science at Merck
39 August 8, 2016 Avi Ma’ayan, Professor, Department of Pharmacology and Systems Therapeutics, Director of the Mount Sinai Center for Bioinformatics, Icahn Medical Institute Mining LINCS Big Data to Knowledge
40 August 8, 2016 Tarek A. Leil, Group Director – Quantitative Clinical Pharmacology, Clinical Pharmacology & Pharmacometrics – Exploratory Clinical and Translational Research (ECTR), Bristol-Meyers Squibb Quantitative Systems Pharmacology (QSP) for Knowledge Integration and Hypothesis Generation in Pharmaceutical R&D
41 August 8, 2016 Robert E. Kass

Maurice Falk Professor of Statistics and Computational Neuroscience

Interim Co-Director

Center for the Neural Basis of Cognition Carnegie Mellon University

Statistical Thinking and Bayesian Thinking in Neuroscience
42 August 8, 2016 Alexandros Makriyannis


George D. Behrakis Endowed Chair

Director of the Center for Drug Discovery

Northeastern University

Control the Deactivation of Cannabinergic Compounds
43 May 17,


Peter Blumberg, PhD.

Chief, Molecular Mechanisms of Tumor Promotion Section

Laboratory of Cancer Biology and Genetics

National Cancer Institute, National Institutes of Health

Because it is never so simple, lessons from the phorbol esters
44 May 13, 2016 Andreas Pfenning, PhD.

Assistant Professor

Computational Biology, Carnegie Mellon University

Genomic insights into the biological basis of behavior
45 April 26, 2016 Alexander DÖmling, PhD.

Professor and Chair

Department of Drug Design,University of Groningen

Expanding chemical space with modern multi-component reactions towards small molecule PD1-PDL1 antagonists
46 April 19, 2016 Brian Blagg, PhD.

Professor of Medicinal Chemistry, University of Kansas

Modern Hsp90 inhibitors from old natural products
47 April 1, 2016 Kunhong (Kevin) Xiao, PhD

Associate Professor

Pharmacology & Chemical Biology

School of Medicine

University of Pittsburgh

Proteomics and Systems Biology of GPCRs: Novel Paths to Drug Discovery
48 March 8, 2016 Cheng Zhang, PhD.

Assistant Professor

Department of Pharmacology and Chemical Biology
School of Medicine, University of Pittsburgh

GPCR structural pharmacology: Structures and Drugs
49 March 21, 2016 Michael Zemaitis, PhD


Pharmaceutical Sciences

School of Pharmacy

University of Pittsburgh

The Current National and State-Wide Landscape of Medical Cannabis
50 Jan 12, 2016 Milos Hauskrecht, PhD.

Professor of Computer Science

Department of Computer Sciences, University of Pittsburgh

Outlier detection for clinical monitoring and alerting
51 Nov 6, 2015 Manojkumar Puthenveedu, PhD.

Associate Professor

Biological Sciences, Carnegie Mellon University

Opioid receptor trafficking – roles in opioid physiology and addiction
52 Nov 3, 2015 Dexi Liu, PhD.

Panoz Professor of Pharmacy, Head

Department of Pharmaceutical and Biomedical Sciences

College of Pharmacy, University of Georgia

Tuning-up gene expression to prevent and treat obesity and obesity-associated insulin resistance
53 Oct 13, 2015 Xianghua Lu, MD, PhD.

Associate Professor

Department of Biomedical Informatics

School of Medicine, University of Pittsburgh

Filling the gaps from cancer genome to personalized therapy: computational precision medicine
54 Oct 2, 2015 Michael Vanyukov, PhD


Departments of Pharmaceutical Sciences, Psychiatry, and Human Genetics

Liability to Drug Addiction


55 Sep 29, 2015 Dandan Sun, MD, PhD.

Professor, Endowed Chair, Brain Disorder Research

Department of Neurology

School of Medicine, University of Pittsburgh

Fish oil DHA reduces ER stress in traumatic brain injury


56 Sep 11, 2015 Mary Torregrossa, PhD.

Assistant Professor

Department of Psychiatry, Translational, Neuroscience Program, University of Pittsburgh

Identification of a Novel Regulatory Site on CaMKIIa Involved in Maintaining Cocaine Associated Memories
57 July 15, 2015 Oscar L. Lopez, M.D.

Departments of Neurology and Psychiatry

School of Medicine, University of Pittsburgh

Long-Term Effects of Conbination therapy in Patients with Alzheimer’s Disease
58 May 14, 2015 Mingfeng Bai, PhD.

Assistant Professor

Department of Radiology

School of Medicine, University of Pittsburgh

Development of a CB2-selective Near Infrared Fluorescent Probe
59 May 14, 2015 Ethan Block, PhD.

Department of cell biology

University of Pittsburgh

Regulation of dopamine transporter function by classical and predicted ligands
60 May 14, 2015 Ralph E. Tarter, PhD.


Pharmaceutical Sciences, University of Pittsburgh

Lifespan Perspective of Drug Addiction
61 May 14, 2015 Mary Torregrossa, PhD.

Assistant Professor

Department of Psychiatry, University of Pittsburgh

Development of Ligands for Memory-Based Treatments for Addiction