Xiang-Qun (Sean) Xie, Ph.D.,EMBA (Director of CDAR and PI of Core A)
Professor of Pharmaceutical Sciences/Drug Discovery Institute
Director of Computational Chemical Genomics Screening Center
Director of NIH NIDA Center of Excellence for Computational Drug Abuse Research
Associate Dean for Research Innovation, School of Pharmacy, University of Pittsburgh
Dr. Wang’ research interest: Chemogenomics/Chemoinformatics database, Structure-based and Ligand-based drug design, Bioinformatics database, Signaling pathway, Data mining & Machine learning algorithms
Ziheng’s research interests include the application of advanced statistical methods and machine learning algorithms on clinical data analysis. Currently, his research focuses on establishing a clinical decision support system to facilitate personalized medicine for Alzheimer’s disease patients with various comorbidities.
Shifan’s research interests focus on computational-aided medicinal chemistry, including molecular docking, pharmacophore, similarity search, design, synthesis and in vitro bio-assay evaluations, predicting targets for natural products, virtual screening.
Changrui’s research interests include: 1) Structural biology and pharmacology of Cannabinoid receptor 2 (CB2). 2) Design, optimization, and validation of CB2 novel agonists and inverse agonists. 3) Molecular mechanism of CB2.
Dr. Bao’s research focus on GBM chemogenomics knowledgebase for systems pharmacology research. Study on material foundation and mechanism of Chinese herbs based on Computer aid drug design and systems pharmacology.
Dr. Ge’s research interests is computational-aided medicinal chemistry, including molecular docking, pharmacophore, design, synthesis and in vitro bio-assay evaluations.