Date Presenter Name Talk Title Annotation
3/3/2020 Jane Aldrich, PhD

Professor

Department of Medicinal Chemistry

University of Florida College of Pharmacy

Novel opioid peptides that don’t follow the rules Core A/School of Pharmacy
1/14/2020 Yaacov Barak, PhD

Associate Professor of Obstetrics

Department of Gynecology and Reproductive Science

Magee-Women’s Research Institute

PPARgamma in Adipocytes: A master regulator of A survival factor? Core A/School of Pharmacy
12/17/2019 Joshua Denny, MD

Professor

Vanderbilt University

School of Medicine

The all of us research program and improving health through big data and engaging diverse populations Core A/School of Pharmacy
11/5/2019 Shyni Varghese, PhD

Professor of Bioengineering, Mechanical Engineering & Materials Sciences and Orthopaedics

Duke University

Pratt School of Engineering

Physicochemical properties of extracellular matrix: key to function, clue to mechanism Core A/School of Pharmacy
9/17/2019 Wayne Backes, PhD

Professor of Pharmacology

LSU Health

New Orleans

School of Medicine

The role of protein-protein and membrane-protein interactions on the organization of P450 systems proteins Core A/School of Pharmacy
7/23/2019 Sarah Harris,
University of Leeds
Multiscale Simulations of Biological Macromolecules: from Atoms to the Continuum Limit Seminar organized by Core B (DCSB)
4/16/2019 Minoli Perera, PharmD, PhD.
Associate professor
Department of Pharmacology
Northwestern University
African Ancestry Pharmaco-omics Seminar organized by Core A (school of pharmacy)
4/16/2019 Lillian Chong,
University of Pittsburgh
The Art of Possibility: Weighted Ensembles of Trajectories Seminar organized by Core B (DCSB)
4/2/2019 Dan Rosenbaum, PhD
Associate professor
Departments of Biophysics and Biochemistry
UT Southwestern Medical Center
Structure and Mechanism of Human CNS GPCRs Seminar organized by Core A (school of pharmacy)
3/26/2019 Patrick Marroum, PhD
Senior Director& Senior Research Fellow
Clinical Pharmacology and Pharmacometrics
AbbVie Inc.
The Role of Modeling and Simulation in Setting Clinically Relevant Specifications Seminar organized by Core A (school of pharmacy)
3/19/2019 Timothy P. Ryan, PhD
Research Fellow
Dyslipidemia and Outcomes Research
Eli Lily and Company, Indianapolis, Indiana
Incorporating Genomic, Clinical, and Real-world Evidence Into Drug Discovery-perspectives and Future Directions Seminar organized by Core A (school of pharmacy)
3/12/2019 Ali Saglam,
University of Pittsburgh
Weighted ensemble sampling of rule-based models Seminar organized by Core B (DCSB)
3/5/2019 Jane M. Liebschutz, MD, MPH, FACVP
Chief, Division of General Internal Medicine
Director, Center for Research on Health Care
University of Pittsburgh School of Medicine
Approach to Opioid Use Disorder in General Medical Settings Seminar organized by Core A (school of pharmacy)
3/29/2019 Florencio Serrano Castillo Multi-Scale QSP Models of Cystic Fibrosis Airway Pathophysiology Seminar organized by Core A
2/26/2019 Yuanyuan Chen,
University of Pittsburgh
The Roles of Rhodopsin Homeostasis and Signaling Seminar organized by Core B (DCSB)
2/12/2019 Weikang Wang,
University of Pittsburgh
Single cell morphology trajectory analysis on cell cycle and Epithelial-to-Mesenchymal transition Seminar organized by Core B (DCSB)
11/20/2018 John Schuetz, PhD
Member, Vice Chair
Department of Pharmaceutical Sciences
St. Jude Children’s Research Hospital
ABC transporters as disease modifiers: Porphyria & cholestasis of pregnancy Seminar organized by Core A (school of pharmacy)
12/18/2018 Olivier Lichtarge,
Baylor College of Medicine
Making Personal Sense of Disease: Machine Learning and Mutational Calculus Seminar organized by Core B (DCSB)
11/13/2018 HongChun Li,
University of Pittsburgh
Improving Protein Sequence Matching to Aid Genome-Based Medicine Seminar organized by Core B (DCSB)
11/6/2018 Yanqiao Zhang, MD,
FAHA Professor
Department of Integrative Medical Sciences
Northeast Ohio Medical University
Role of miR-34a in cardiometabolic diseases Seminar organized by Core A (school of pharmacy)
10/30/2018 Amy Newman, PhD
Deputy Scientific Director
Medication Development Program
Chief, Molecular Targets and Medications Discovery Branch
NIDA-IRP/NIH
Design of bitopic ligands with dopamine D2 receptor Bias Seminar organized by Core A (school of pharmacy)
10/30/2018 Luca Ponzoni,
University of Pittsburgh
Integrated Approach for Pathogenicity Prediction of Missense Variants Seminar organized by Core B (DCSB)
10/30/2018 James Krieger,
University of Pittsburgh
Normal Mode Sampling Simulations and Electron Microscopy Image Analysis Seminar organized by Core B (DCSB)
10/16/2018 David Boulton, PhD
Executive Director
Quantitative Clinical Pharmacology
AstraZeneca
The role of clinical pharmacology in drug development: Dapagliflozin, a novel SGLT2 inhibitor, as an example Seminar organized by Core A (school of pharmacy)
10/2/2018 Kai Tan, PHD
Associate Professor
Department of Pediatrics and Department of Biomedical and Health Informatics
The Children’s Hospital of Philadelphia
University of Pennsylvania
Optimal control nodes in disease-perturbed networks as targets for combination therapy Seminar organized by Core A (school of pharmacy)
5/22/2018 Ruiwen Zhang, MD, PhD, DABT, FAAAS
Professor of Pharmacology and Toxicology
Robert L. Boblitt Endowed Professor in Drug Discovery
Director of UH Center for Drug Discovery
Targeting p53-MDM2 pathway: implication in cancer and neurogenerative diseases Seminar organized by Core A (school of pharmacy)
4/25/2018 Velvet (Blair) Journigan, PhD
Assistant Professor of Medicinal Chemistry
Department of Pharmaceutical Sciences
Marshall University School of Pharmacy
Structure-based design of novel small molecule ligands for the transient receptor potential melastatin 8 (TRPM8) ion channel: Insights and applications from recent structural biology advances Seminar organized by Core A (school of pharmacy)
3/21/2018 Mary Torregrossa, PhD
Assoc. Prof.,
Psychiatry, Translational Neuroscience Program,
University of Pittsburgh
Identification of Novel Regulators of Cocaine-Associated Memories New FRP
1/8/2018 Inmaculada Hernandez, PharmD, PhD
Assistant Professor
Department of Pharmaceutical Sciences
University of Pittsburgh
Real-world Use, Outcomes, and (Value-based?) Pricing of Pharmaceuticals: An Overview of My Research Program New P/FP
1/8/2018 Philip Empey, PharmD, PhD
Assistant Professor
Department of Pharmaceutical Sciences
University of Pittsburgh
Pharmacogenomics to achieve precision medicine at Pitt/UPMC New P/FP
12/11/2017 Andreas Pfenning, PhD
Assistant Professor
Department of Computational Biology
Carnegie Mellon University
Interpreting addiction-associated genetic variation at regulatory elements New FRP
11/10/2017 Min Xu, PhD
Research Assistant Professor
Department of Computational Biology
Carnegie Mellon University
Structural mining in cellular electron cryo-tomograms New P/FP
10/12/2017 Zachary Freyberg, PhD
Assistant Professor
Departments of Psychiatry and Cell Biology
University of Pittsburgh
New Cryo-EM Approaches to the Study of Secretory Cell Biology New P/FP
5/2/2017 Robert Roth, PhD, DABT
Professor of Pharmacology and Toxicology
Director, Graduate Program in Environmental and Integrative Toxicological Sciences
Michigan State University
Drug-cytokine interaction in idiosyncratic, drug-delivered liver injury Seminar organized by Core A (school of pharmacy)
4/24/2017 Xiaoyuan (Shawn) Chen, PhD
Senior Investigator and Chief
Laboratory of Molecular and Nanomedicine
National Institute of Biomedical Imaging and Bioengineering
National Institutes of Health
Nanomedicine for imaging and therapy Seminar organized by Core A (school of pharmacy)
4/18/2017 Ram Mahato, PhD
Professor and Chair
Department of Pharmaceutical Sciences
University of Nebraska Medical Center
Gene and stem cell therapy for improving islet transplantation in humanized mice Seminar organized by Core A (school of pharmacy)
4/13/2017 Robert A. Sweet, MD
UPMC Endowed Chair & Prof.,
Psychiatric Neuroscience and Neurology
Investigating the Mechanisms of Psychosis New FRP
4/11/2017 Susan Slaugenhaupt, PhD
Professor of Neurology
Center for Human Genetic Research
Massachusetts General Hospital
Harvard Medical School
Developing a drug for an mRNA splicing disease Seminar organized by Core A (school of pharmacy)
4/4/2017 Aiming Yu, PhD
Professor
Director of the PK/PD Bioanalytical Core Facility
Department of Biochemistry and Molecular Medicine
UC Davis School of Medicine
Translating microRNA pharmacoepigenetics into therapy Seminar organized by Core A (school of pharmacy)
3/14/2017 Seth Corey, MD, PhD
Professor and Chief
Children’s Hospital Foundation
Endowed Chair in pediatric Cancer Research
Virginia Commonwealth University
School of Medicine
Pediatric Myelodysplastic Syndromes: A Gain of Clones Seminar organized by Core A (school of pharmacy)
3/3/2017 Howard Gutstein, PhD
Peter & Eva Safar Prof. and Chair, Anesthiology, Upitt
Zero Tolerance for Chronic Pain Seminar organized by Core A (school of pharmacy)
2/17/2017 Ming Hu, PhD
Professor of Pharmaceutics
University of Houston College of Pharmacy
Challenges facing CNS delivery of polyphenols and flavonoids Seminar organized by Core A (school of pharmacy)
2/14/2017 Edward Prochownik, MD, PhD
The Paul C. Gaffney Professor of Pediatrics and Professor of Microbiology & Molecular Genetics Section of Hematology/Oncology
Rangos Research Center
School of Medicine
Cancer as a Ribosomopathy Seminar organized by Core A (school of pharmacy)
1/23/2017 Nicholas Meanwell, PhD
Executive Director
Department of Medicinal Chemistry
Bristol-Myers Squibb
Pharmaceutical Research and Development
NS5A inhibitors of hepatitis C Seminar organized by Core A (school of pharmacy)
12/13/2016 Nathan A. Yates
Associate Professor, Department of Cell Biology
Scientific Director, Biomedical Mass Spectrometry Center
Schools of the Health Sciences
University of Pittsburgh
Application of Differential Mass Spectrometry for the Unbiased Identification of CSF Biomarkers and Novel Protein Targets Seminar organized by Core A (school of pharmacy)
12/13/2016 Jacob D. Durrant, PhD
Assistant Professor
Department of Biological Sciences
University of Pittsburgh
Computer-Aided Drug Design: From Basic Science to Clinical Applications Seminar organized by Core A (school of pharmacy)
12/8/2016 Dandan Sun, MD, PhD
Professor
Department of Neurology
School of Medicine
University of Pittsburgh
Ion transporters: new targets for glioma therapy Seminar organized by Core A
11/29/2016 Min You, PhD
Professor
Department of Pharmaceutical Sciences
College of Pharmacy
Northeastern Ohio Medical University
Lipin-1 signaling and its implications in the alcoholic fatty liver Seminar organized by Core A (school of pharmacy)
11/8/2016 Dharini Shah, PhD
Principal Scientist
Center for Therapeutic Innovation
Pfizer
Adventures in drug discovery: Case studies on immune checkpoint as therapies Seminar organized by Core A (school of pharmacy)
11/1/2016 Edward A. Burton, MD, DPhil FRCP
Associate Professor of Neurology, Microbiology and Molecular Genetics
UPMC Endowed Chair in Movement Disorders
School of Medicine
University of Pittsburgh
Drug discovery for neurodegenerative diseases using novel zebrafish models Seminar organized by Core A (school of pharmacy)
10/11/2016 Gavin Arteel, PhD
Professor, Associate Chair for Research
Department of Pharmacology and Toxicology
University of Louisville School of Medicine
Transitional changes to the hepatic “matrisome” in the development of inflammatory liver injury Seminar organized by Core A (school of pharmacy)
10/4/2016 Moses Turkle Bility, PhD
Assistant Professor
Department of Infectious Diseases and Microbiology
Graduate School of Public Health
University of Pittsburgh
Modeling human pharmacogenomics in humanized mice Seminar organized by Core A (school of pharmacy)
9/27/2016 Dexing Zeng, PhD
Professor, Molecular Imaging Laboratory
Department of Medicine
University of Pittsburgh
Dual-receptor targeting for enhance PET imaging Seminar organized by Core A (school of pharmacy)
9/7/2016 Raman Venkataramanan, PhD
Professor
Dept. of Pharmaceutical Sciences, School of Pharmacy
Dept. of Pathology, School of Medicine
University of Pittsburgh
Modeling of PK and PD data in clinical pharmacology Seminar organized by Core A (school of pharmacy)
8/8/2016 Christopher K. Surratt,
Professor of Pharmacology,
Mylan School of Pharmacy,
Duquesne University
Do the behavioral effects of dopamine transporter (DAT) inhibitors correlate with DAT conformation preference? Seminar organized by Core A (school of pharmacy)
8/8/2016 Kevin Xiao,
Associate Professor,
Department of Pharmacology and Chemical Biology,
University of Pittsburgh
Defining the Higher Order Structures of  GPCR Signaling Complexes for Drug Discovery Seminar organized by Core A (school of pharmacy)
8/8/2016 Joshua Yohannan, MS,
Laboratory Manager
The Allegheny County Medical Examiner’s Office
AB vs ADB: One Methyl Makes a Large Difference Seminar organized by Core A (school of pharmacy)
8/8/2016 Manojkumar Puthenveedu,
Associate Professor,
Biological Sciences and The Center for the Neural Basis of Cognition,
Carnegie Mellon University
New strategies to manage opioid addiction and pain Seminar organized by Core A (school of pharmacy)
8/8/2016 Sally E. Wenzel,
Professor of Medicine & Director
University of Pittsburgh Asthma Institute
b2-Adrenergic Receptor Responses and Asthma:   Modulation through Protein-Lipid Interactions Seminar organized by Core A (school of pharmacy)
8/8/2016 Youhua Liu,
Professor,
Department of Pathology,
University of Pittsburgh
Targeting Cannabinoid Receptor-2 to Reduce Renal Fibrosis Seminar organized by Core A (school of pharmacy)
8/8/2016 Rao Rapaka,
Branch Chief of NIH NIDA
NIDA’s Basic Chemistry Research and Translational Areas of Interest Seminar organized by Core A (school of pharmacy)
8/8/2016 Steven D. Shapiro,
Executive Vice President, UPMC
Chief Medical and Scientific Officer
UPMC’s Big Data Initiative Seminar organized by Core A (school of pharmacy)
8/8/2016 Christopher Waller,
Executive Director
MRLIT Modeling Platformsand CORE
Merck
Translational Data Science at Merck
8/8/2016 Avi Ma’ayan,
Professor,
Department of Pharmacology and Systems Therapeutics,
Director of the Mount Sinai Center for Bioinformatics,
Icahn Medical Institute
Mining LINCS Big Data to Knowledge
8/8/2016 Tarek A. Leil,
Group Director
Quantitative Clinical Pharmacology,
Clinical Pharmacology & Pharmacometrics
Exploratory Clinical and Translational Research (ECTR),
Bristol-Meyers Squibb
Quantitative Systems Pharmacology (QSP) for Knowledge Integration and Hypothesis Generation in Pharmaceutical R&D Seminar organized by Core A (school of pharmacy)
8/8/2016 Robert E. Kass
Maurice Falk Professor of Statistics and Computational Neuroscience
Interim Co-Director
Center for the Neural Basis of Cognition Carnegie Mellon University
Statistical Thinking and Bayesian Thinking in Neuroscience Seminar organized by Core A (school of pharmacy)
8/8/2016 Alexandros Makriyannis
Professor
George D. Behrakis Endowed Chair
Director of the Center for Drug Discovery
Northeastern University
Control the Deactivation of Cannabinergic Compounds Seminar organized by Core A (school of pharmacy)
5/17/2016 Peter Blumberg, PhD.
Chief, Molecular Mechanisms of Tumor Promotion Section
Laboratory of Cancer Biology and Genetics
National Cancer Institute, National Institutes of Health
Because it is never so simple, lessons from the phorbol esters Seminar organized by Core A (school of pharmacy)
5/13/2016 Andreas Pfenning, PhD.
Assistant Professor
Computational Biology,
Carnegie Mellon University
Genomic insights into the biological basis of behavior
4/26/2016 Alexander DÖmling, PhD.
Professor and Chair
Department of Drug Design,
University of Groningen
Expanding chemical space with modern multi-component reactions towards small molecule PD1-PDL1 antagonists Seminar organized by Core A (school of pharmacy)
4/19/2016 Brian Blagg, PhD.
Professor of Medicinal Chemistry,
University of Kansas
Modern Hsp90 inhibitors from old natural products Seminar organized by Core A (school of pharmacy)
4/1/2016 Kunhong (Kevin) Xiao, PhD
Associate Professor
Pharmacology & Chemical Biology
School of Medicine
University of Pittsburgh
Proteomics and Systems Biology of GPCRs: Novel Paths to Drug Discovery Seminar organized by Core A (school of pharmacy)
3/8/2016 Cheng Zhang, PhD.
Assistant Professor
Department of Pharmacology and Chemical Biology
School of Medicine,
University of Pittsburgh
GPCR structural pharmacology: Structures and Drugs Seminar organized by Core A (school of pharmacy)
3/21/2016 Michael Zemaitis, PhD
Professor
Pharmaceutical Sciences
School of Pharmacy
University of Pittsburgh
The Current National and State-Wide Landscape of Medical Cannabis Seminar organized by Core A (school of pharmacy)
1/12/2016 Milos Hauskrecht, PhD.
Professor of Computer Science
Department of Computer Sciences,
University of Pittsburgh
Outlier detection for clinical monitoring and alerting Seminar organized by Core A (school of pharmacy)
11/6/2015 Manojkumar Puthenveedu, PhD.
Associate Professor
Biological Sciences,
Carnegie Mellon University
Opioid receptor trafficking – roles in opioid physiology and addiction Seminar organized by Core A (school of pharmacy)
11/3/2015 Dexi Liu, PhD.
Panoz Professor of Pharmacy, Head
Department of Pharmaceutical and Biomedical Sciences
College of Pharmacy, University of Georgia
Tuning-up gene expression to prevent and treat obesity and obesity-associated insulin resistance Seminar organized by Core A (school of pharmacy)
10/13/2015 Xianghua Lu, MD, PhD.
Associate Professor
Department of Biomedical Informatics
School of Medicine, University of Pittsburgh
Filling the gaps from cancer genome to personalized therapy: computational precision medicine Seminar organized by Core A (school of pharmacy)
10/2/2015 Michael Vanyukov, PhD
Professor
Departments of Pharmaceutical Sciences, Psychiatry, and Human Genetics
Liability to Drug Addiction Seminar organized by Core A (school of pharmacy)
9/29/2015 Dandan Sun, MD, PhD.
Professor, Endowed Chair, Brain Disorder Research
Department of Neurology
School of Medicine, University of Pittsburgh
Fish oil DHA reduces ER stress in traumatic brain injury Seminar organized by Core A (school of pharmacy)
9/11/2015 Mary Torregrossa, PhD.
Assistant Professor
Department of Psychiatry, Translational, Neuroscience Program,
University of Pittsburgh
Identification of a Novel Regulatory Site on CaMKIIa Involved in Maintaining Cocaine Associated Memories Seminar organized by Core A (school of pharmacy)
7/15/2015 Oscar L. Lopez, M.D.
Departments of Neurology and Psychiatry
School of Medicine, University of Pittsburgh
Long-Term Effects of Conbination therapy in Patients with Alzheimer’s Disease Seminar organized by Core A (school of pharmacy)
5/14/2015 Mingfeng Bai, PhD.
Assistant Professor
Department of Radiology
School of Medicine, University of Pittsburgh
Development of a CB2-selective Near Infrared Fluorescent Probe Seminar organized by Core A (school of pharmacy)
5/14/2015 Ethan Block, PhD.
Department of cell biology
University of Pittsburgh
Regulation of dopamine transporter function by classical and predicted ligands Seminar organized by Core A (school of pharmacy)
5/14/2015 Ralph E. Tarter, PhD.
Professor
Pharmaceutical Sciences, University of Pittsburgh
Lifespan Perspective of Drug Addiction Seminar organized by Core A (school of pharmacy)
5/14/2015 Mary Torregrossa, PhD.
Assistant Professor
Department of Psychiatry, University of Pittsburgh
Development of Ligands for Memory-Based Treatments for Addiction Seminar organized by Core A (school of pharmacy)